Burger Fusion Company (La Crosse, WI)
Travelers can try a gourmet smash burger close to the Mississippi River. Ingredients are locally and regionally sourced as well.
Pete’s Hamburger Stand (Prairie du Chien, WI)
During the warmer months, this stand opens its doors and serves classic burgers to hungry lines. In fact, the stand has been a local favorite since 1909.
Central Standard Burgers (Bettendorf, IA)
Want to try something new? This burger stop has eclectic options for those trying to mix it up with their taste buds.
Boonie’s on the Avenue (Muscatine, IA)
Sports fans will appreciate Muscatine’s favorite burger joint and sports bar. Their specialty burger options and classic bar foods are go-tos for game day.
Tuggers (Port Byron, IL)
Tuggers claims they can fulfill your ‘burger lust’ with their unique options. Some notable burger names include Mighty Miss Triple, River Queen, and Rope Burn!
Steel Plow Burger Company (Moline, IL)
These burgers are made of grass-fed beef. Try their specialty burgers, or build your own!
Mary Jane Burgers & Brew (Perryville, MO)
Mother knows best, but so does grandma Mary Jane! The burgers are locally sourced and thirsty eaters can select from a diverse beer list.
Gordon’s Stoplight Drive-In (Crystal City, MO)
Gordon’s Quadzilla burger was featured in FEAST Magazine under “9 MUST TRY burgers in St.Louis”. They have one mission: to serve the best hamburger at the most affordable price.
Just Hamburgers (Paducah, KY)
This stop is for the hungry budget travelers! Try their The Red’s Zeppelin, which is a double bacon cheeseburger with two glazed donuts as buns.
Beehive Cafe (Clinton, KY)
The mac and cheese burger resides in western Kentucky! Although they serve a variety of foods, the burger selection will cause travelers to swarm the hive.
Huey’s Restaurant (Memphis, TN)
Huey’s is a southwestern Tennessee chain that connects burgers, beer, and live music. The restaurant is also voted “Best Burger” by Memphis Magazine.
Dave’s on the Square (Dyersburg, TN)
Dave’s signature buns and hand pattied meat makes a great local stop in north west Tennessee. Reviews claim the burgers are nothing short of amazing.
Tacker’s Shake Shack (Marion, AR)
The restaurant has been featured in Southern Living and it’s on the Arkansas Pie Trail, so be sure to save room for dessert.
Rhoda’s Famous Hot Tamales (Lake Village, AR)
Despite the name (and video above), the tamale food stop serves great burgers! This restaurant is also cash-only, so come prepared.
The Tomato Place (Vicksburg, MS)
Try the classic BLT burger in an old fashioned stand near the road. They also offer a southern classic—po’boys!
Blue and White (Tunica, MS)
Since 1924, the diner serves a variety of burgers and breakfast foods for hungry quick-stop travelers. The Mississippi version of a BLT is a DBLFGT (double dacon, lettuce, fried green tomatoes).
Our Mom’s Restaurant and Bar (Baton Rouge, LA)
Think of the best southern food dishes made into a burger! The restaurant offers a fried pickle burger and a boudin burger.
Twisted Burgers (Plaquemine, LA)
Want a serving of southern hospitality with your burger? This riverside stop is a favorite among locals and newcomers for their burgers and the friendly staff.